National University Corporation Chiba University;Nissan Chemical Industries, Ltd.
发明人:
申请号：
EP11795711.8
公开号：
EP2581442A1
申请日:
2011.06.13
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
An expanding agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful as a therapy for various hematopoietic diseases and useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy is provided.A method of producing hematopoietic stem cells and/or hematopoietic progenitor cells, which comprises expanding hematopoietic stem cells by culturing hematopoietic stem cells ex vivo in the presence of a compound represented by the formula following (I), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof (wherein R1 to R6 are as defined in the description).
