Herein provided is a new wheat cultivar designated ‘GA 041293-11E54’ as well as the seeds, plants and derivatives of the new wheat variety ‘GA 041293-11E54’ (such as cultivars and hybrids related thereto). This cultivar is a high grain yielding, medium maturing, good test weight, medium height line that has good resistance to races of leaf rust and stripe rust in Georgia and the Southeast, powdery mildew, Hessian flies, and wheat soil-borne mosaic virus. Also provided are tissue cultures of the new wheat variety ‘GA 041293-11E54’ and the plants regenerated therefrom. Methods for producing wheat plants by crossing the new wheat variety ‘GA 041293-11E54’ with itself or another wheat variety and plants produced by such methods are also provided.
