ACINETOBACTER O-OLIGOSACCHARYLTRANSFERASES AND USES THEREOF

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专利权人:

VAXNEWMO LLC

发明人:

FELDMAN, MARIO,NASR, MOHAMED ADEL

申请号：

CA2977561

公开号：

CA2977561A1

申请日:

2016.02.26

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present application provides methods and uses of O-oligosaccharyltransferase (O-OTases) for generating vaccines. In particular, the present application provides a method of synthesizing a glycoprotein comprising glycosylation of pilin-like protein ComP using a Pg1LComP O-OTase. Uses of glycoproteins synthesized by glycosylating Com P using Pg1LComP O-OTase, particularly for the preparation of vaccines and the like, including a vaccine to Streptococcus, is also provided.

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