As for the composite membrane which relates to this invention, the base material which consists of hydrophilic high-molecular in (B), the hydrophobic macromolecule being the composite membrane which (A) was applied, the said hydrophobic macromolecule the surface of the said features that it exists inside base material and/or. In addition, the iontohuoreshisu device which relates to this invention, the operation side electrode of the operation side electrode structure, the non operation side electrode structure, and the said operation side electrode structure to have the direct voltage source which is jointed with the polarity which differs between the non operation side electrodes of the said non operation side electrode structure, being the iontohuoreshisu device in order to prescribe the ionicity medicine to the living body with the said direct voltage source, the said non operation side electrode structure to have the said non operation side electrode and the non operation side electrolyte attaching part, on the one hand, the said operation side electrode structure the said operation side electrode and electrolyte containmentThe liquid medicine attaching part, and the said electrolyte attaching part containment the section and the said ionicity medicine it possesses the diaphragm which is laid out between the said liquid medicine attaching part, it features that the said diaphragm is the aforementioned composite membrane.本発明に係る複合膜は、親水性高分子からなる支持体(B)に、疎水性高分子(A)を塗布した複合膜であって、該疎水性高分子が該支持体の表面及び/又は内部に存在することを特徴とする。また、本発明に係るイオントフォレーシス装置は、作用側電極構造体、非作用側電極構造体、並びに該作用側電極構造体の作用側電極と該非作用側電極構造体の非作用側電極の間に異なる極性で接続される直流電源を有し、該直流電源により、イオン性薬剤を生体に投与するためのイオントフォレーシス装置であって、該非作用側電極構造体は該非作用側電極と非作用側電解液保持部を有し、一方、該作用側電極構造体は該作用側電極と電解液保持部と該イオン性薬剤を保持する薬液保持部、及び該電解液保持部と該薬液保持部の間に配置された隔膜を有し、該隔膜が前記複合膜であることを特徴とする。
