An acoustic ventilator using feedback control is designed to generate and exert a desired mixture of pressure oscillations into a supply of gas entering a subjects airways to maintain optimal ventilation and perfusion in the lungs. According to the subjects biological specifications and real-time medical condition, computers and human interface control the vibrations in intensity and frequency along with the pressure and composition of blended gases in order to enhance oxygenation and CO2 clearance. Acoustic ventilation will cause the ventilating gases to diffuse through the subjects lungs without the aid of a separate ventilator, and with or without spontaneous breathing.