The disclosure relates to a stable anthelmintic composition in the form of a micellar solution, comprising an anthelmintically effective amount of at least two anthelmintic agents, wherein one anthelmintic agent is a macrocyclic lactone selected from the group consisting of: abamectin, ivermectin, doramectin, moxidectin, milbemycin and/or avermectin, and the other anthelmintic agent is an imidazothiazole selected from the group consisting of: levamisole, pyrantel pamoate and butamisole at least one surfactant a solvent system comprising water and one or more water miscible solvent(s) selected from the group consisting of one or more polyethylene glycols, tetraglycol, ethanol, benzyl alcohol and propylene glycol and a buffering system to adjust the pH of the composition to a range of about 5 to 5.5.