A portable dispenser assembly for dispensing disinfectant to a user. The assembly includes a main housing defining a cavity for receiving a container in an inverted position. The main housing defines an opening into the cavity through which the container is inserted in the inverted position so that a stem of the container is directed downwardly in the main housing. The main housing including a bottom wall, a side wall, and a nozzle fixed with respect to the walls. The nozzle defines an inlet opposite the opening for receiving the stem of the container in the inverted position and the nozzle defines a discharge aperture configured to direct the disinfectant fluid from the container toward the user when the user depresses the container relative to the main housing to dispense the disinfectant fluid from the container.