DERIVES DE BISPHENOL ET LEUR UTILISATION EN TANT QUE MODULATEURS DE L'ACTIVITE DU RECEPTEUR DES ANDROGENES

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专利权人:

THE UNIVERSITY OF BRITISH COLUMBIA;BRITISH COLUMBIA CANCER AGENCY BRANCH

发明人:

ANDERSEN, RAYMOND,SADAR, MARIANNE DOROTHY,JIAN, KUNZHONG,MAWJI, NASRIN R.,WANG, JUN,BANUELOS, CARMEN ADRIANA,YANG, YU-CHI

申请号：

CA3021008

公开号：

CA3021008A1

申请日:

2017.04.18

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Compounds having a structure of Formula I or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R11a, R11b, R11c, R11d, and X, are as defined herein, are provided. Uses of such compounds for modulating androgen receptor activity, imaging diagnostics in cancer and therapeutics, and methods for treatment of subjects in need thereof, including prostate cancer are also provided.

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中国工程科技知识中心

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http://www.ckcest.cn/home/