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Method for producing megakaryocytes and/or platelets from pluripotent stem cells
专利权人:
发明人:
NISHINO TAITO,NAKAMURA TAKANORI,IWAMOTO SHUNSUKE,ETO KOJI,NAKAUCHI HIROMITSU,TSUJI KAYOKO
申请号:
IN3536/DELNP/2014
公开号:
IN2014DN03536A
申请日:
2014.05.01
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
Provided is an inducing agent for megakaryocytes and/or platelets from pluripotent stem cells the inducing agent being useful in treating diseases involving thrombopenia. A method for producing megakaryocytes and/or platelets the method comprising: separating hematopoietic progenitor cells and cells that form a septum of a net like structure produced by pluripotent stem cells, in the presence of a compound represented by formula (I) (R^R 7, W, X, Y, Z, Ar 1, and n in the formula are defined in the specification), a tautomer of the compound a prodrug, a pharmaceutically acceptable salt of these, or a solvate of these compounds culturing the resulting hematopoietic progenitor cells in vitro and differentiating the same into megakaryocytes and/or platelets.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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