CRAWFORD PATTI C,GIBBS PAUL J,DUBOVI EDWARD J,DONIS RUBEN O,KATZ JACQUELINE,KLIMOV ALEXANDER I,LAKSHMANAN NALLAKANNU P,LUM MELISSA ANNE,GOOVAERTS DANIEL GHISLENA EMIEL,MELLENCAMP MARK WILLIAM,COX NANC
申请号：
NZ60766706
公开号：
NZ607667A
申请日:
2006.10.19
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed is a recombinant viral vector comprising a polynucleotide encoding a hemagglutinin (HA) comprising the amino acid sequence shown in SEQ ID NO:62, or a functional and/or immunogenic fragment thereof, or said polynucleotide encodes a polypeptide having 98% or greater sequence identity with the amino acid sequence shown in SEQ ID NO: 62, wherein the sequence is as defined in the complete specification. Also disclosed is a canine influenza vaccine, wherein the vaccine comprises a therapeutically effective amount of an influenza virus that is capable of infecting a canid animal, wherein said influenza virus comprises: i) a polynucleotide which encodes a polypeptide having the amino acid sequence shown in SEQ ID NO: 62, or a functional and/or immunogenic fragment thereof, or said polynucleotide encodes a polypeptide having 98% or greater sequence identity with the amino acid sequence shown in SEQ ID NO: 62 or ii) a polypeptide having the amino acid sequence shown in SEQ ID NO: 62, or a functional and/or immunogenic fragment thereof, or said polynucleotide encodes a polypeptide having 98% or greater sequence identity with the amino acid sequence shown in SEQ ID NO: 62.
