AYERS MARK D,LOBODA ANDREY,LUNCEFORD JARED K,MCCLANAHAN TERRILL K,MURPHY ERIC E,NEBOZHYN MICHAEL
申请号:
IN201747019501
公开号:
IN201747019501A
申请日:
2017.06.02
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
A gene expression platform which is a combination of a set of genes that are correlated with response to a PD 1 antagonist in multiple tumor types and a normalization gene set is disclosed. A method and system of using the gene expression platform to derive gene signature biomarkers of anti tumor response to a PD 1 antagonist and to test patient samples for predictive gene signature biomarkers are also disclosed.