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91pde אם שידרה של אימידזו–פירזינון
专利权人:
H. LUNDBECK A/S
发明人:
申请号:
IL23783615
公开号:
IL237836A
申请日:
2015.03.19
申请国别(地区):
IL
年份:
2017
代理人:
摘要:
This invention is directed to 6-[4-METHYL-1-(PYRlMIDIN-2-YLMETHYL)PYRROLIDIN-3-YL]-3-TETRAHYDROPYRAN-4-YL-7H-IMIDAZO[1,5-A]PYRAZIN-8-ONE and pharmaceutically acceptable acid addition salts thereof, which are PDE9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of invention. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of the invention. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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