ADAMS, NICHOLAS D,亚当斯,亞當斯,BURGESS, JOELLE LORRAINE,柏格斯,DARCY, MICHAEL GERARD,戴麦克,戴麥克,DONATELLI, CARLA A,德奈特,KNIGHT, STEVEN DAVID,史帝芬,NEWLANDER, KENNETH ALLEN,钮兰德,鈕蘭德,RIDGERS, LANCE,里格斯
申请号：
TW097117926
公开号：
TWI410417B
申请日:
2008.05.16
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
Invented is a method of inhibiting the activity/function of PI3 kinases using quinoline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoline derivatives.本發明係有關一種採用喹啉衍生物抑制PI3激酶之活性/功能之方法。本發明亦有關藉由投與喹啉衍生物來治療一種或多種選自下列之疾病之方法：自體免疫病變、發炎疾病、心血管疾病、神經變性疾病、過敏、氣喘、胰炎、多重器官衰竭、腎臟疾病、血小板凝集、癌症、精子活動力、移植排斥、移植物排斥及肺部傷害。
