Liliana A. Miinea,Elena S. Draganoiu,Kedar V. Chikhalikar,Vikrant V. Chadawar
申请号：
US16609912
公开号：
US20200113839A1
申请日:
2018.05.01
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The disclosed technology provides improved drug compositions that provide increased stability, higher drug loading potential, and suitable drug dissolution properties, and methods of making the same. The composition include: (a) a drug component comprising a therapeutically effective amount of a drug； (b) an extended release component comprising a cross-linked polyacrylic acid polymer that is a carbomer homopolymer, carbomer copolymer, carbomer interpolymer, polycarbophil or a mixture thereof； and (c) a buffering component comprising a magnesium containing buffering agent； wherein the drug component makes up at least 50% by weight of the composition.
