POLYMERIC SYSTEMS CONTAINING INTRACELLULAR RELEASABLE DISULFIDE LINKER FOR THE DELIVERY OF OLIGONUCLEOTIDES

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专利权人:

ENZON PHARMACEUTICALS; INC.

发明人:

ZHAO, HONG,REDDY, PRASANNA

申请号：

EP09751640

公开号：

EP2288261A4

申请日:

2009.05.22

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention provides polymeric prodrugs including an intracellular releasable disulfide linker for the delivery of oligonucleotides. Methods of making the compounds as well as methods of delivering nucleic acids to tumor cells in a mammal using the same are also provided.

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