Dennis W. Goupil,Hassan Chaouk,Troy Holland,Bruktawit T. Asfaw,Stephen D. Goodrich,Lucas Latini
申请号:
US14659377
公开号:
USRE047873E1
申请日:
2015.03.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as embolic agents to block and fill lumens and spaces. The embolic compositions can be used as liquid embolic agents and crosslinked in situ or as preformed embolic articles, such as microspheres.