PROF. DATIN PADUKA DR. KHATIJAH MOHD YUSOF,ASSOC. PROF. DR. ABDUL RAHMAN OMAR,ZPROF. AINI IDERIS,MOHAMED RAJIK
申请号：
MYPI 20082061
公开号：
MY160435A
申请日:
2008.06.12
申请国别(地区):
MY
年份:
2017
代理人:
摘要：
THE PRESENT INVENTION RELATES TO RECOMBINANT PHAGES CARRYING FUSION PEPTIDES THAT BIND TO AVIAN INFLUENZA VIRUS (AIV). SUCH PHAGES ARE USEFUL AS DIAGNOSTIC REAGENTS TO REPLACE ANTI-AIV ANTIBODIES BECAUSE THE PHAGES ARE CAPABLE OF COMPETING WITH THE LATTER ANTIBODIES FOR BINDING SITES ON THE VIRUS. SYNTHETIC PEPTIDES WITH THE SEQUENCE CNDFRSKTC, EITHER IN LINEAR OR CYCLIC CONFORMATIONS, OR FUSION PHAGES BEARING THE ABOVE SAID PEPTIDES INHIBITED AIV PROPAGATION IN EMBRYONATED EGG AS WELL AS IN MDCK CELL LINES. THEREFORE THEY MAY BE USED ASTHERAPEUTIC AGENTS TO CONTROL, TO TREAT AND TO ERADICATE BIRD FLU CAUSED BY AVIAN INFLUENZA VIRUS.
