The preparation of a kind of 20(R)-ginsenoside Rg3 medicinal compositionaqueous solution containingginsenoside Rg3 0.5 - 10 mg/ml: add 0.1-5% of ginsenoside solution to 0.1 -30% of adjuvant A, B125at the temperature of 40 - 100°C, the ratio of these two is 1:1 - 300,add water after the solvent is recycledunder reduced pressure; another kind of 20(R)-ginsenoside Rg3 medicinalcomposition aqueous solutioncontains 0.1 - 2mg/ml of 20 (R) of the ginsenoside Rg3, the preparation: add0.1 - 5% of ginsenosidesolution to 20 - 65% of adjuvant B34 at the temperature of 60 - 100°C,main material to adjuvantB=1:100 - 400, add water after the solvent is recycled under reduced pressure.The above 20 (R)ginsenoside Rg3 composition aqueous solution and the powder afterlyophilizaton can be used to prepareinjectable, oral administration and external use, and the bioactivity of thesepreparations is high, and withthe actions of anti cancer, efficacy potentiation and toxicity attenuationeffects of the combined chemical orradiation therapy of tumor, enhancement of human immune functions, improvementof human memory,anti fatigue, and detumescence, pain relieving.