Anthony Phillips,David Eisenbud,Scott Bannan,David Pool,Grove Matsuoka,Tracey Sunderland,Bradford Duft
申请号:
US13844762
公开号:
US09156896B2
申请日:
2013.03.15
申请国别(地区):
US
年份:
2015
代理人:
摘要:
This invention concerns improved methods, uses, and kits for treating chronic wounds through the administration of anti-connexin agents, particularly anti-connexin 43 antisense polynucleotides. The methods, uses, and kits of the invention are based on the surprising and unexpected discovery that chronic wounds that do not increase or decrease in size by more than a pre-determined amount during a pre-treatment phase are more amenable to successful treatment than wounds whose size varies outside the target range during the pre-treatment phase.