CASTAIGNE, JEAN-PAUL,DEMEULE, MICHEL,CHE, CHRISTIAN,REGINA, ANTHONY
申请号:
EP10821522
公开号:
EP2486061A4
申请日:
2010.10.05
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention is directed to conjugates that include a polypeptide capable of crossing the blood-brain barrier or entering one or more cell types attached to a transport vector, i.e., a composition capable of transporting an agent (e.g., a therapeutic agent). In certain cases, the polypeptides are directly conjugated to a lipid or polymeric vector to allow targeted application of a therapeutic agent to treat, for example, a cancer, a neurodegenerative disease, or a lysosomal storage disorder.