Disclosed herein are compositions and systems having a low coefficient of friction. The low friction system comprises a first surface and a second surface, where the first surface comprises (i) a polycarbonate and a first additive, or (ii) a polybutylene terephthalate and a second additive； and the second surface comprises a polyoxymethylene and a third additive. The low friction compositions and systems are valuable for producing devices, such as medical devices.
