The present invention relates to a composition comprising ex-vivo expanded adipose tissue derived stem cell (ASC) or ex-vivo expanded adipose tissue-derived stem cells (ASC) mixed with harvested fat tissue at a ratio of 5,0 x 10 4 - 2,0 x 10 ASCs/mL fat for example 1,0 x 10 5 - 2,0 x 10 7 and the use of ex-vivo expanded adipose tissue-derived stem cells or ex-vivo expan ded adipose tissue- derived stem cell enriched fat grafts as an agent for cosmetic breast filling/augmentation or for facial filling/reju - venation.
