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FULVESTRANT NANOSPHERE/MICROSPHERE AND PREPARATIVE METHOD AND USE THEREOF
专利权人:
发明人:
申请号:
EP09848593.1
公开号:
EP2417975A1
申请日:
2009.08.31
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Fulvestrant nanosphere/microsphere and preparation method and use thereof are provided in the present invention. The carrier material of the fulvestrant nanosphere /microsphere is methoxy ended polyethylene glycol-polylactic acid block copolymer. The nanosphere/microsphere is prepared by solvent-nonsolvent method, in-liquid drying method and/or spray drying method, and has the features of high drug loading and high encapsulation efficiency, controllable release of medicine and no irritant to application site or blood vessel. The fulvestrant nanosphere/microsphere can be used to treat metastatic advanced breast cancer in post-menopausal woman.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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