A composition for topical application comprising: -at least one sucrose stearate comprising at least 70% by weight of monoesters of sucrose and of stearic acid, the rest being composed of diesters, triesters and polyesters of sucrose and of stearic acid, -and/or a sorbitan ester, for use in the therapeutic treatment of cutaneous atopy, as an agent for inhibiting the adhesion of Staphylococcus aureus to human nasal mucosa and skin.