An opthalmic system (100) having an opthalmic cassette (104) for operative engagement with an opthalmic apparatus (102) is disclosed. The opthalmic cassette (104) includes a cassette body (108) having a manifold (124) defining an inlet port (180) in fluid flow communication with first and second fluid pathways (120/122) which are in selective fluid flow communication with respective first and second storage chambers (116/118) such that fluid enters either the first storage chamber (116) or the second storage chamber (118). The opthalmic apparatus (102) is operable to permit alternate fluid flow communication between the inlet port (108) and either the first storage chamber (116) or the second storage chamber (118) during operation of the opthalmic system (100).