IMBA - INSTITUT FUR MOLEKULARE BIOTECHNOLOGIE GMBH;MEDIZINISCHE UNIVERSITAT WIEN
发明人:
PENNINGER, JOSEF,WIRNSBERGER, GERALD,ZWOLANEK, FLORIAN,KUCHLER, KARL
申请号:
CA3026998
公开号:
CA3026998A1
申请日:
2017.06.09
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention relates to the prevention or treatment of diseases by regulating innate immunity. The present invention provides a Cbl-family inhibitor for use in the prevention or treatment of diseases in a patient, a Cbl-family inhibitor comprising a binding peptide of Syk, a fusion peptide comprising a cell delivery portion and a Cbl-family TKB domain binding peptide, wherein the Cbl-family TKB domain binding peptide binds to the TKB domain of a Cbl-family protein, kits and uses for the same.