MAYRI ALEJANDRA DIAZ DE, RIENZO,ANDREW STEPHEN, JAMIESON,PAUL SIMON, STEVENSON
申请号：
TR201909226
公开号：
TR201909226T4
申请日:
2014.12.16
申请国别(地区):
TR
年份:
2019
代理人:
摘要：
Refers to piperidiniltetrahidroquinolinas substituted Derivatives of formula (i) wherein R1, R2, R3 and R4 are as defined in the description.Preferred compounds are: [4 - (4 - dihidroisoquinolin - 2 (1H) - il) piperidin-1-yl] [2 - (6 - [3 - azaespiro Oxa.3] hept-3-ene - 6 - il) pyrimidin-5-yl] methanone； [4 - (7 - fluoro - 3.4 - dihidroisoquinolin - 2 (1H) - il) piperidin-1-yl] [2 - (oxa - 6 - azaespiro [3.3] hept-3-ene IL - 6 - pyrimidin-2-yl) - 5 - il] methanone； among others.It also relates to a preparation method and a Pharmaceutical composition.These compounds are antagonists of alpha adrenergic receptor 2C being useful for the treatment of diabetic microangiopatias thromboembolic DisordersMevcut buluş, bir ramnolipid içeren geliştirilmiş bir bakterisit bileşime ilişkindir.
