KOJIMA Hiroyuki,MIYAZAKI Masakazu,NISHIURA Mare,NISHIZATO Takashi
申请号:
PH12016502285
公开号:
PH12016502285A1
申请日:
2016.11.16
申请国别(地区):
PH
年份:
2017
代理人:
摘要:
Provided is a pharmaceutical composition for oral administration enabling size reduction and improved solubility, elutability, and oral absorbability of (2R)-N-({5-[3-(2,5-difluorophenyl)-2-(1,3-dihydro-2H-benzimidazole-2-ylidene)-3-oxopropanoyl]-2-fluorophenyl} sulfonyl)-2-hydroxypropane imide-amide (hereafter, compound A) or a pharmaceutically acceptable salt thereof. The pharmaceutical composition for oral administration contains a polymer or amorphous form of compound A or a pharmaceutically acceptable salt thereof.