METHODS OF GENERATING HYPER INOS EXPRESSING CELLS AND USES THEREOF

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专利权人:

发明人:

Kurt Q. Lu,Kevin D. Cooper

申请号：

US13780503

公开号：

US20140170165A1

申请日:

2013.02.28

申请国别(地区):

US

年份:

2014

代理人:

摘要：

A method of generating a hyper iNOS expressing cell includes administering to a myeloid derived cell an amount of a PPARγ agonist and an IL-6/STAT3 signaling pathway antagonist effective to substantially inhibit STAT3 activation in the cell and administering an inflammatory insult to the cell to stimulate hyper iNOS expression from the cell.

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