Selexys Pharmaceuticals Corporation;Oklahoma Medical Research Foundation
发明人:
Rodger P. McEver,Richard Alvarez,Ziad Kawar
申请号：
US13757405
公开号：
US09556266B2
申请日:
2013.02.01
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention features antibodies, e.g., chimeric and humanized antibodies, that recognize (i.e., bind) P-selectin. The P-selectin antibodies prevent P-selectin from binding to its cognate receptor. The P-selectin antibodies can be used to treat inflammatory and thrombotic conditions, e.g., sickle cell disease, pain crisis associated with sickle cell disease, deep vein thrombosis, asthma, rheumatoid arthritis, psoriasis, and ischemia reperfusion injury in a patient in need thereof.
