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RECOMBINANT RSV ANTIGENS, NUCLEIC ACID MOLECULES ENCODING THE ANTIGENS, AND VACCINE COMPOSITIONS COMPRISING THE SAME
专利权人:
Limin Huang
发明人:
Limin Huang,Jenmin Huang
申请号:
US16462757
公开号:
US20190314491A1
申请日:
2017.11.22
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided is an antigen including a recombinant respiratory syncytial virus (RSV) F protein, wherein the recombinant RSV F protein includes an antigenic region flanked with an HRN region and an HRC region, and the antigenic region includes one or more antigenic sites selected from the group consisting of site Ø, site II, and site IV. The present disclosure also provides a nucleic acid molecule encoding the antigen and a vaccine composition including the antigen for eliciting an immune response against RSV.
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