Geoffrey T. Yarranton;Christopher R. Bebbington;David King;Lesley B. Pickford
发明人:
Lesley B. Pickford,Christopher R. Bebbington,Geoffrey T. Yarranton,David King
申请号：
US13050601
公开号：
US08828393B2
申请日:
2011.03.17
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Compositions and methods for the therapy of Inflammatory Bowel Disease (IBD), including Celiac Disease, Crohn's Disease, and Ulcerative Colitis, are disclosed. Illustrative compositions comprise one or more anti-type 1 interferon antagonists, such as anti-type 1 interferon receptor antibody antagonists and fragments thereof, as well as polypeptides and small molecules that inhibit the interaction of type 1 interferon with its receptor (IFNAR).
