Shanghai Hengrui Pharmaceutical Co., Ltd.;Jiangsu Hengrui Medicine Co., Ltd.
发明人:
Jingjing FANG,Zhen YAN,Guimei TONG,Xun LIU
申请号：
US16618974
公开号：
US20200129633A1
申请日:
2018.06.05
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A stable c-Met antibody-drug conjugate (c-Met ADC) formulation and use thereof in medicine are described. In particular, the formulation contains c-Met ADC, a buffer, and can also contains at least one stabilizer, and optionally a surfactant. The c-Met ADC formulation of the application can effectively inhibit the aggregation and isomerization of antibodies, and prevent the degradation of an antibody product therein, being a stable injectable pharmaceutical formulation.
