Vaccines for protection from and treatment of alzheimers disease

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专利权人:

发明人:

Bira Arya,Richard Markham

申请号：

US14152782

公开号：

US09433665B2

申请日:

2014.01.10

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Disclosed herein are DNA-based vaccines against amyloid β peptide for use in treating and alleviating Alzheimers Disease and related conditions. A DNA construct comprising DNA encoding one or more amyloid β peptides, such as amino acids 1-11 of Aβ, and DNA encoding a hepatitis B antigens, is administered with an adjuvant or by electroporation. The vaccine can also be formulated using a fusion protein expressed by the disclosed DNA, in combination with an adjuvant.

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http://www.ckcest.cn/home/