Them are handled in the case that non-activated stem cell is by having a wavelength of the range for being 405 to 980 nanometers in the laser beam of an amplitude modulation to be activated. Laser beam is modulated in the range of 8 to 12 MHz. With active stem cell, by preparing non-activated stem cell, tissue can be repaired and make, have a pre-determined frequency for handling non-activated stem cell in the case where obtaining active stem cell in the laser beam of an amplitude modulation, active stem cell is managed into the main body comprising tissue, guides active stem cell within main body to the position of tissue using a home beam.