BERRY, Jody,MELTON WITT, Jody,SON, Sodany,BAUMEISTER, Mark
申请号：
AU2018366480
公开号：
AU2018366480A1
申请日:
2018.11.16
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
Various embodiments of the invention relate to polypeptides comprising 1-10 or more epitopes of the HIV envelope protein and a fusion protein, wherein the polypeptide lacks the transmembrane domain of the HIV gp41 protein. Such polypeptides may be expressed in mammalian cells, such as human cells, to produce, for example, polypeptides that are useful in developing novel anti-HIV antibodies. Polypeptides described herein and novel antibodies developed therefrom are generally useful for medical diagnostics, and they may also be useful in the prophylactic and therapeutic treatment of HIV.
