BREITENBACH, JOERG, DR.,HEGER, ROBERT, DR.,SIMON, DIRK, DR.,LIEPOLD, BERND, DR.
申请号：
EP99117238.8
公开号：
EP0987549B1
申请日:
1999.09.02
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
Testsystem zur Charakterisierung der Verträglichkeit von biologisch aktiven Substanzen mit Polyvinylpyrrolidonen in einer Feststoffdispersion, bestehend aus einer oder mehreren biologisch aktiven Substanzen und 1,3-Bis-(pyrrolidon-1-yl)-butan.1,3-Bis(pyrrolidon-1-yl) butane (I) is used as a dispersant or solvent in a test system for characterising the compatibiity of biologically active substances with polyvinylpyrrolidone (PVP) in a solid dispersion. Independent claims are also included for the following: (1) a test system for characterising the compatibility of biologically active substances with PVP in a solid dispersion, consisting of one or more biologically active substances and (I) (2) a method for characterising the compatibility of biologically active substances with PVP in a solid dispersion, comprising dissolving or dispersing one or more biologically active substances in (I) and spectroscopically evaluating the solution or dispersion.
