DR SHAILESH SINGH,DR BHARAT SUTTAR,DR ASHISH JAIN,VINOD GAIKWAD,KULDIP KULKARNI
申请号：
IN1262/MUM/2012
公开号：
IN2012MU01262A
申请日:
2012.04.20
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
A process for the preparation of Roflumilast formula-I comprising, preparation of anion of 4-amino-3, 5-dichloropyridine formula-Ill and in-situ reaction of anion of 4-amino-3, 5-dichloropyridine formula-Ill with activated compound of 3-cyclopropylmethoxy-4-difluromethoxybenzoic acid formula-V, followed by purification to obtain pure Roflumilast.
