A condition change determination method and condition change determination apparatus that, when a medical person uses a method for determining a condition change of a patient, such as NEWS, can accurately determine the condition of the patient, and a program and computer readable medium that are to be used in the apparatus or the method are provided. A non-transitory computer readable medium including a program causes a computer to realize the functions of: acquiring at least one of apnea and hypopnea rates of a patient; acquiring vital signs information of the patient other than the apnea and hypopnea rates; and determining a condition change of the patient by a determination method for determining a condition change of a patient based on at least one of the apnea and hypopnea rates, and the vital signs information other than the apnea and hypopnea rates.