Gerard, Daniel E.,Schoelkopf, Joachim,Gane, Patrick A.C.,Stirnimann, Tanja,Alles, Rainer,Puchkov, Maxim,Huwyler, Jörg
申请号:
HRP20191082
公开号:
HRP20191082T1
申请日:
2019.06.17
申请国别(地区):
HR
年份:
2019
代理人:
摘要:
An orally fast disintegrating dosage forms comprising functionalized natural or synthetic calcium carbonate, at least one active ingredient and at least one disintegrant, wherein said functionalized natural or synthetic calcium carbonate is a reaction product of natural or synthetic calcium carbonate with carbon dioxide and one or more acids, wherein the carbon dioxide is formed in situ by the acid treatment and/or is supplied from an external source, and wherein the tablet dissolves in less than 20 seconds when introduced into an aqueous environment.