XIAO Shouhua,PAN Zheng,WICKRAMASINGHE Dineli,JEFFRIES M. Shawn,KING Chadwick Terence,CHAN Brian Mingtung,KUFER Peter,LUTTERBUESE Ralf,RAUM Tobias,HOFFMANN Patrick,RAU Doris,KISCHEL Roman,LEMON Bryan,W
申请号：
SI201431390
公开号：
SI2948477T1
申请日:
2014.01.27
申请国别(地区):
SI
年份:
2019
代理人:
摘要：
The present invention provides to a antibody construct comprising a first human binding domain capable of binding to human CDH19 on the surface of a target cell and a second domain capable of binding to human CD3 on the surface of a T cell. Moreover, the invention relates to a nucleic acid sequence encoding the antibody construct, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention relates a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.
