Robert A. Brodsky;Richard J. Jones;Francis E. O'Donnell, JR.;Susan Bonitz;Carlos Santos;Adam Kaplin
发明人:
Robert A. Brodsky,Richard J. Jones,Francis E. O'Donnell, JR.,Susan Bonitz,Carlos Santos,Adam Kaplin,Francis E. ODonnell, JR.
申请号:
US13240465
公开号:
US20120128685A1
申请日:
2011.09.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to methods of treating an autoimmune disorder, using a lymphocytotoxic but hematopoeitic cell sparing high-dose pulsed amount of an oxazaphosphorine drug in combination with immune therapeutics such as, for example, monoclonal antibodies that selectively bind B-cell specific antigens.