PROBLEM TO BE SOLVED: To provide a hypertension medication excellent as a drug for treatment/prevention of hypertension.SOLUTION: A pharmaceutical agent includes a compound represented by general formula (I) and the like. In the formula: R1 is H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted cyclic hydrocarbon, an optionally substituted heterocyclyl or the like R2 is H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted cycloalkyl or the like R3 and R4 are independently H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted cycloalkyl or the like R5 and R6 are independently H, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted alkoxy or the like R7 and R8 are independently H, an optionally substituted alkyl, an optionally substituted cycloalkyl or the like X is a group represented by formula (II) or the like A is an optionally substituted cyclic hydrocarbon, an optionally substituted heterocyclyl or the like Y is a single bond, an optionally substituted alkylene, an optionally substituted alkenylene, -(CH2)a-X1-(CH2)b- (wherein X1 is -NH-, -O- or the like, and a and b are respectively a number of 0-5) or the like and B is an optionally substituted cyclic hydrocarbon, an optionally substituted heterocyclyl or the like.COPYRIGHT: (C)2013,JPO&INPIT【課題】優れた高血圧症治療薬の提供。【解決手段】一般式(I)[式中、R1:H、置換可アルキル、置換可アルケニル、置換可環状炭化水素、置換可ヘテロシクリル等;R2:H、置換可アルキル、置換可アルケニル、置換可シクロアルキル等;R3、R4;H、置換可アルキル、置換可アルケニル、置換可シクロアルキル等;R5、R6:H、置換可アルキル、置換可シクロアルキル、置換可アルコキシ等;R7、R8:H、置換可アルキル、置換可シクロアルキル等;X:式(II)等;A:置換可環状炭化水素、置換可ヘテロシクリル等;Y:単結合、置換可アルキレン、置換可アルケニレン、-(CH2)a-X1-(CH2)b-(X1:式-NH-、-O-等;a、b:0-5)等;B:置換可環状炭化水素、置換可ヘテロシクリル等]を有する化合物等を含有する。【選択図】なし
