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Substituted 1-benzylquinoxalin-2(1H)-one analogs as positive allosteric modulators of muscarinic acetylcholine receptor M1
专利权人:
发明人:
Craig W. Lindsley,P. Jeffrey Conn,Shaun R. Stauffer,Joseph David Panarese
申请号:
US14787717
公开号:
US09527834B2
申请日:
2014.04.28
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to substituted 1-benzylquinoxalin-2(1H)-one analogs, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M1 (mAChR M1) methods for making the compounds pharmaceutical compositions and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction. Exemplary 1-benzylquinoxalin-2(1H)-one compounds include compounds of the following formula:
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