JONASSEN, THOMAS, ENGELBRECHT NORKILD,NIELSEN, SOREN,FROEKIAER, JOERGEN,LARSEN, BJARNE DUE
申请号:
CA2620228
公开号:
CA2620228C
申请日:
2005.08.26
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The invention describes peptide analogues of a-melanocyte-stimulating hormone(a-MSH), which posses an increased efficay compared to the native .alpha.-MSHpeptide. The .alpha.-MSH analogues exhibit increased anti-inflammatory effectsand increased capability to prevent ischemic conditions compared to .alpha.-MSH. The invention further discloses use of the peptides for the manufactureof pharmaceutical compositions for the treatment or prophylaxis of a conditionin the tissue of one or more organs of a mammal, and moreover pharmaceuticalcompositions.