THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM;THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA;OLA, Antonius;S.M. YEE, Samantha
发明人:
MOOBERRY, Susan, L.,RISINGER, April, L.,CICHEWICZ, Robert, H.,DU, Lin,LI, Jing,PENG, Jiangnan
申请号:
USUS2017/066779
公开号:
WO2018/112391A8
申请日:
2017.12.15
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure relates to the fields of medicine and pharmaceuticals. In particular, the invention relates to the identification of epoxytaccalonolide microtubule stabilizers for use in inhibiting cell proliferation and disrupting normal cellular microtubule processes leading to cell death. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.L'invention concerne les domaines de la médecine et des produits pharmaceutiques. Elle concerne en particulier l'identification de stabilisateurs époxytaccalonolides de microtubules utilisables pour inhiber la prolifération cellulaire et perturber des processus de microtubules cellulaires normaux conduisant à la mort cellulaire....