The present invention relates to a composition for promoting blood circulation, a composition for preventing blood vessel aging, a composition for treating vascular inflammation, a composition for promoting angiogenesis, a composition for treating ischemic heart disease, and a composition for improving and treating local blood flow deficiency, which comprises ginseng fruit extract as an effective ingredient More specifically, the present invention relates to a pharmaceutical composition containing ginseng fruit extract as an active ingredient to promote the production of nitrogen monoxide (NO) in vascular endothelial cells, promote the survival of vascular endothelial cells, increase vascular endothelial cell mobility, To promote angiogenesis.본 발명은 인삼열매 추출물을 유효성분으로 함유하는 혈행촉진용 조성물, 혈관노화방지용 조성물, 혈관염증치료용 조성물, 혈관생성촉진용 조성물, 허혈성 심질환 치료용 조성물 및 국부 혈류부족 개선 및 치료용 조성물에 관한 발명으로서, 더욱 상세하게는, 인삼열매 추출물을 유효성분으로 함유하여 혈관내피세포에서 일산화질소(NO)생성을 촉진시키고, 혈관내피세포의 생존을 증진시키며, 혈관내피세포의 이동성 증가와 혈관튜브생성을 통한 혈관신생을 촉진시키는 조성물에 관한 발명이다.
