BIESSEN, ERIK ANNA LEONARDUS,APPELDOORN, CHANTAL CATHARINA MARIA,BONNEFOY, ARNAUD,VAN BERKEL, THEODORUS JOSEPHUS CORNELIS,KUIPER, JOHAN,HOYLAERTS, MARC FLORIMOND
申请号：
CA2527141
公开号：
CA2527141C
申请日:
2004.05.07
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
Polyhydroxy phenols, which are non-peptidic mimetics of galloyl peptides, anda process for the preparation of gallic acid derivatives using a gallic-acidproviding moiety are provided as well as polyhydroxy phenol-containingpharmaceutical and nutraceutical compositions. The use of polyhydroxy phenolsas a medicament and especially for the manufacture of a medicament for theprevention, treatment or diagnosis of a disease or a condition, wherein P-selectin is involved, is provided. The same compounds can also be used astargeting tools to P-selectin expressing cells or tissues in a composition,further comprising an active compound in a vehicle.
