A catheter (10) includes a handle (12), a catheter sheath (14) and a stylet (20) having a shaped distal part received within the catheter sheath (14). The catheter (10) further has a shape adjustment mechanism (128) including a stylet carrier (104) displaceably carried by the handle and a shape adjuster in the form of a collar (132) rotable about the handle. Rotational movement of the shape adjuster imparts a motion to the stylet carrier to adjust the shape of the distal part of the stylet.