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STABILISATION D'UNE COMPOSITION DIAGNOSTIQUE AUX RAYONS X
专利权人:
GE HEALTHCARE AS
发明人:
GLOGARD, CHRISTIAN,THANING, MIKKEL,CERVENKA, JAN
申请号:
CA2858961
公开号:
CA2858961A1
申请日:
2012.12.20
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The invention relates to a composition comprising a non-ionic X-ray contrast agent in a pharmaceutically acceptable carrier, and particularly to a supersaturated X-ray composition comprising X-ray contrast agents with a high dissolution temperature in water. Particularly, the invention provides such composition which is stable, and wherein crystallisation during storage is avoided. In a preferred aspect the X-ray contrast agent is Ioforminol and the composition includes a nucleation-and growth inhibitor. The invention further relates to a process for the preparation of such stable diagnostic X-ray composition.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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